PUFA Protect (Vitamin E)

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Pure Vitamin E in a base of MCT Oil with mixed tocopherols. One of the primary ways that excessive polyunsaturated fats (PUFAs) break down healthy tissue is by depleting them of Vitamin E.

Without adequate vitamin E, lipid propagation occurs where a non-ending chain of oxidized PUFAs are made that ultimately damage cells and tissues, forming lipofuscin after years of oxidative stress. 

BENEFITS of Vitamin E:

  • Supports tissue oxygenation*
  • Reduces oxidation of lipid membranes by PUFAs*
  • Protects against lipid peroxidation*
  • Increases conversion of linoleic acid (PUFA) into saturated fat*
  • Protects skin loaded with PUFAs from ultraviolet sun damage*
  • Improves circulation*
  • Improves mitochondrial respiration*
  • Protects from free radical damage*
  • Opposes all negative effects of estrogen*
  • Decreases vitamin A burn rate*
  • Decreases progesterone burn rate*
  • Protects against calcification and iron overload*
  • Supports the turnover of vitamin C. 
  • Supports glutathione production. 
  • Helps with glucose metabolism.

Among so many additional roles… 

The common person would classify omega-3s as "healthy fats", omega-6s as "bad fats" and saturated fat as something to avoid or limit. 

Unsaturated fats are long chains with multiple double bonds that don't contain as many hydrogen atoms as saturated fats. 

What does this mean in English? They are more prone to oxidation.

This process overall is called lipid peroxidation. Excess iron stored in the tissues is one of many potential triggers that initiates the process. The chain reaction (called the Fenton reaction) creates cancer-causing products such as acrolein and leads to cancer, diabetes, heart disease, heart attacks, non-alcoholic fatty liver disease, aging, depression, anxiety, fatigue, Alzheimer's disease, dementia, skin conditions, autoimmune disorders and more. 

Vitamin E was discovered in 1922 by H.M. Evans and K.S. Bishop. It is one of the major fat soluble vitamins that are required for vital health along with vitamin A, D, and K. Of those four vitamins, vitamin E is the hardest to find. 

Nature built it into all foods that contain polyunsaturated fatty acids (PUFAs). Vitamin E is in grassfed beef, nuts, seeds, fish, shellfish and grains. The only thing is that vitamin E is lost when foods are heated. Most people consume cooked nuts and seeds so we aren't even getting small amounts of vitamin E that way. 

Contrary to what we often hear, it is very safe to supplement.* Doses up to 3,000 IU/mg a day have been used to improve eye conditions [1, 2] and mental retardation [1, 2].* While PUFAs, especially omega-3s, cause muscular dystrophy, vitamin E may help to improve it.*

Dr. Shute was the one that pioneered high dose vitamin E, using it to help more than 20,000 of his patients with conditions ranging from heart disease to infertility (both of which are caused by excess PUFAs).

Vitamin E increases the conversion of linoleic acid into saturated fat. It protects the skin from ultraviolet light which increases lipid peroxidation when it reacts with PUFAs. It protects against many of the damaging effects of excess iron and calcium. 


You're eating outside of the home with friends and family and you don't want to be that person micromanaging every ingredient that goes into the meal. You're with a large group of people and some of them are not as health conscious as you. It is okay to let go every once in a while and not care when you're out enjoying good company. But if you're healing from a chronic condition or just want to be on the top of your game, you still partake but have Mitolife PUFA Protect in a small ziplock bag that you take with you to lunch and dinner. 

This vitamin E extract will protect your cells from the ravages of lipid peroxidation. It contains not only d-alpha tocopherol, the form used in most of the studies, but also mixed tocopherols, including beta, gamma, and delta which make it more of a whole-food extract. 

This potentiates the vitamin E and provides a robust concoction of molecules that essentially supercharge the vitamin E’s antioxidant capabilities! 

Or you can use it like Matt Blackburn, the founder of Mitolife does, to help decrease stress and mitigate any damage that could be caused while the PUFA gets out of the tissues. It takes about four years to detoxify excess polyunsaturated fats from your tissues.


Displace them with saturated fats, supplement vitamin E, consume carbohydrates consistently, consume animal protein consistently and do everything you can to lower the amount of stressors while increasing your resilience to stress. The liver needs glycogen to detox PUFAs and the body needs vitamin E because PUFAs create a vitamin E deficiency. We have been consuming them in large amounts our entire lives! 

Three capsules contain 1,332 mg of mixed tocopherols, mostly from d-alpha tocopherol and gamma tocopherol, with trace amounts of beta and delta tocopherol.


Relationship between vitamin E requirement and polyunsaturated fatty acid intake in man: a review.

Vitamin E function and requirements in relation to PUFA.

On the problematic nature of vitamin E requirements: net vitamin E.

Medium chain triglycerides and vitamin E reduce the severity of established experimental alcoholic liver disease.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any diseases.

Customer Reviews

Based on 272 reviews
Stephanie Cancienne (Covington, US)
Quality product

I love this product but don’t like that it went from one daily to 3 (even if they are smaller). I feel like I got more for my money before the change.

Amanda Nogradi (Rogersville, US)
Vitamin E

I have struggled with hormone imbalance for the past 2 years. I started taking 3 of these vitamin E capsules per day, and my progesterone levels automatically increased in 3 days! I am more than thrilled! I have done seed cycling and so many other things. This is my go to now for hormone support.

U.K. (Central Point, US)
Life changing

This has truly changed my life…I have suffered with debilitating menstrual pain for 28 years and now I’ve been pain-free for almost a year! I’m still in complete awe…amazing product, Matt! Thank you so much.

Chesley (Brooklyn, US)
Vitamin e

I swear since I started using this my skin looks glowier and acne scars are fading. It’s only been 30 days and I just started taking the full dose. I started slowly because I was afraid of upset stomach or acne that can come with taking vit e but I got none of that. Love it

Jenae Hart (Glenside, US)
PUFA Protect

Like some other reviewers, my digestive system has had a hard time with these. Even if I just took one capsule with a meal, it still made things move real fast through my GI tract. The only way I can take it is by cutting open one capsule and mixing it with something like yogurt.

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