Probiotic & Endotoxin Reducer

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Endotoxin, or lipopolysaccharide, is a molecule that's bound to intestinal bacteria. When they die, it is released. Under normal circumstances the liver and intestines can quickly eliminate it, but with polyunsaturated fat (PUFA) build-up in the liver and a lifetime of excessive fiber consumption, most people are compromised.

Low stomach acid, hypothyroidism (carbohydrate or animal protein restriction), stress, intermittent fasting, ketogenic diets, and stress all create a build-up of endotoxin.


You experiences allergies (food or environmental), autoimmune conditions, acne, eczema, rashes, constipation, diarrhea, acid reflux, infertility, menstrual dysfunction, irritable bowel disorder, diabetes, arthritis, migraines, edema, insomnia, poor sleep quality, energy dips, depression, anxiety, obsessive compulsive disorder, psychosis, the list goes on!


When the system is compromised and cannot eliminate endotoxin, it passes through the intestinal wall, enters circulation and spreads throughout the entire system. Endotoxin itself increases intestinal permeability. Glyphosate is just a small piece of the puzzle! Got stress? Restricting carbohydrate or animal protein? Low HCL?


The primary mechanism that we use to detoxify stored PUFAs from the liver is called glucuronidation, and this process is inhibited by endotoxin (Bánhegyi, et al, 1995).

Ulcerative colitis (UC) and Crohn's disease (CD) [inflammatory bowel disease (IBD) all have endotoxin in common (Caradonna, et al., 2000).

Endotoxin increases liver and organ damage from alcohol (Purohit, et al., 2008). 

Circulating lipopolysaccharide significantly increased in chronically HIV-infected individuals (Brenchley, et al., 2006). 

Endotoxin suppresses the thyroid gland, the immune system and leads to an increase in nitric oxide and the stress hormones estrogen, serotonin and prolactin, which further increase endotoxin production.


"Spore based" is just another way of saying "Soil based". They are microorganisms that are formed from spores. You can get these same strains in the dirt or on vegetables with dirt residue. They are just concentrated in this supplement and you know exactly what you're getting.

A study conducted by the World Journal of Gastrointestinal Pathophysiology found that just 30 (thirty!) days of spore-based probiotic oral supplementation reduced endotoxin by 42% (Mcfarlin, et al., 2017). They also saw a 24% reduction in triglycerides and a decrease in systemic inflammation markers. The subjects took two capsules a day.

They used five strains including Bacillus clausii, Bacillus subtilis, Bacillus coagulans, the strains included in the Mitolife Probiotic. We chose to omit the carotenoid-producing strain as carotenoids have been demonstrated to suppress thyroid function if they accumulate in the tissues. 

Bacillus bacteria are gram-positive instead of the endotoxin producing gram-negative bacteria. They can be found in animal guts, air, water and soil. They have the ability to make various antimicrobial and antibiotic-like compounds (Elshaghabee, et al., 2017). They also have immuno-modulatory and anti-mutagenic effects.  

Like minerals, there are a lot of them, but only a handful make a difference.

Bacillus subtilis has even been studied as a prevention for diabetes. The researchers found that it protected the beta cells of the pancreas, leading to decreased blood glucose levels (Zouari, et al., 2015). 


The formula also contains a small amount of Fructooligosaccharides. This compound occurs naturally in plants and consists of a string of fructose units. They are very safe and stimulate the growth of nonpathogenic gut bacteria.


You can take one capsule with breakfast and one at night with dinner. They can also be taken on an empty stomach. Time of day when you take them doesn't matter. 

Supporting your metabolism with food frequency and balanced meals helps to reduce endotoxin buildup. Do not restrict sugar (carbohydrates) or animal protein. Let's get those endotoxin levels down! 


Probiotic Blend - 5 Billion CFU, Bacillus coagulans, Bacillus subtilis, Bacillus clausii, Prebiotic, FOS (Fructooligosaccharides) 

 *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any diseases.

Customer Reviews

Based on 25 reviews
Sara T (Chula Vista, US)
Love this product

I absolutely love this product! I’ve had gut issues my whole life and have tried many products. Having Hasimoto’s and a sluggish metabolism, and I’m sure lots of endotoxins…I had learned to live with a lower bar of expectations for my gut health.
I finally quit smoking 6 months ago, and I didn’t have any lung issues- but I had the worst nausea, constipation, and indigestion imaginable. I tried everything:: store bought enzymes, probiotics, laxatives - nothing worked until I started using this product. Total game changer!

Mychel (Honolulu, US)
Underwhelmed by product

Again I have been taking these for almost two weeks now and don't feel any difference. No negative or positive effects at all. I'm kind of disappointed because I take shilajit and absolutely feel the difference it makes. I was hoping for the same results from these probiotics but no such luck. I will up my daily dosage in a few days and take till I run out of this bottle as well since I don't seem to be experiencing any negative side effects. Hopefully I will feel some positive effects with a higher dose. If not I will not purchase this again.

Anonymous (Denver, US)
Repair your Gut

I have been taking these for 2 months now. I feel like i am a new person. I am not suffering from the severe acid reflux i usually deal with every day. I am about to order another bottle. I will probably take these for the rest of my life.

Jacqueline Garcia (Los Angeles, US)
Highly reccommend

I’ve been taking this for a month and have definitely noticed a difference. I take it right before breakfast. I had amennorhea for a year and a half and a CLF/ray peat style diet the past 3 weeks combined with this, the shilajit, dissolve it all and daily raw carrot salad got me my period back in about 3-4 weeks. Would highly reccomend and plan to continue using.

Myra Gazvoda (Denver, US)
Most Trusted

I take this if I eat a meal with a steak to help my pancreas. And have recently started taking it with my daily carrot salad!